Altered methylation pattern of the SRD5A2 gene in cerebrospinal fluid of post-finasteride patients: a pilot study.
https://www.ncbi.nlm.nih.gov/m/pubmed/31272082/
Neuroactive steroid levels and psychiatric and andrological features in post-finasteride patients. https://www.ncbi.nlm.nih.gov/m/pubmed/28408350/?i=2&from=/31272082/related
These studies find big drops in CSF levels of oestradiol and DHT in CSF (together responsible for libido/sexual function) and also dihyrdoprogesterone (not sure what this does).
The top one also finds altered methylation of the 5AR2 gene in half of the PFS patients.
I don't know where we would have to send CSF samples to have these tests done. Figuring that out is the next step.
https://www.ncbi.nlm.nih.gov/m/pubmed/31272082/
Neuroactive steroid levels and psychiatric and andrological features in post-finasteride patients. https://www.ncbi.nlm.nih.gov/m/pubmed/28408350/?i=2&from=/31272082/related
These studies find big drops in CSF levels of oestradiol and DHT in CSF (together responsible for libido/sexual function) and also dihyrdoprogesterone (not sure what this does).
The top one also finds altered methylation of the 5AR2 gene in half of the PFS patients.
I don't know where we would have to send CSF samples to have these tests done. Figuring that out is the next step.