THEORY - PAS and PFS - 5-Alpha Reductase Enzyme - Very Plausible/Currently seems to be the most likely cause of PAS

Jan 25, 2021
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#21
The only partial recovery I have found is from Mifepristone. Hang in there mate.
Thanks for your reply! Can i ask how long and how much dosage have you used that medicine? Which doctor should i go for taking this medicine?
And i want to say that i am taking 200 mg of Panax Ginseng daily, at first week i felt almost healed. I gained the pleasure and orgasm almost fully but in 2nd week it all became worse again... Maybe that can help for short duration.
 

Perene

New member
Feb 16, 2021
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#22
This thread is very interesting since I reported in the Acne forum * that my blood levels of (note: needs to be logged for you to see, otherwise it may show as removed):

* Post #1 / Post #2 / Post #3 / Post #4 / Post #5 / Post #6 / Post #7

- DHT
- LH
- FSH
- Free testosterone
- Estradiol
- Prolactin

Are all messed up probably due to my 2011 Accutane treatment that lasted months. As you can see, low estradiol for men means low libido (from what I understood, it can't be too high or too low - never one of the extremes!): https://www.nejm.org/doi/full/10.1056/NEJMoa1206168

Low LH, FSH, DHT, all mean low libido, too. Prolactin in the 20's (should be half that for a man) is another sign of sexual dysfunction.

What I hypothesized is that adding these supplements:

- Peruvian MACA, Tribulus Terrestris, Fenugreek, Tongkat Ali, D-Aspartic Acid...

May perhaps make a difference by increasing both estrogen and testosterone levels. And perhaps also others like DHT, LH, FSH... and decreasing prolactin.

Also thinking of adding Panax ginseng.

Besides probably low libido due to Accutane use I also had (this was 100% confirmed) severe depression. The depression probably lasted for a few years, before it was gone forever. It has been said this was probably due to vitamin B12 depletion. My blood tests showed my B12 levels to be OK.

Link for the study (Decreased vitamin B 12 and folic acid concentrations in acne patients after isotretinoin therapy: A controlled study)

Low vitamin B12 accounts for this:

- Mental problems like depression, memory loss, or behavioral changes.

EDIT: in post #6 (see above) I added a few studies supporting these supplements as a good idea to boost libido/testosterone. I also asked a question about DHT: if Accutane supresses it, and high DHT equals having ACNE, then shouldn't that imply that "curing" acne means becoming impotent? At least for some...
 
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